Metastatic neuroendocrine tumour of the orbit

A 64-year-old patient presented with a tumour of the orbit. A biopsy showed an infiltrative tumour with coarse “salt-and-pepper” chromatin, showing strong expression of AE1/3, CD56, synaptophysin, chromogranin, and CDX2 on immunohistochemistry. The Ki67 proliferation index was low (<1%). The diagnosis of metastatic neuroendocrine tumour, most likely of gastrointestinal origin was favoured over a primary neuroendocrine tumour of the orbit.

Citation

Hunter, H., & Thomas, M. (2024). Metastatic neuroendocrine tumour of the orbit. Diagnostic Histopathology, 30(3), 188–190. https://doi.org/10.1016/j.mpdhp.2023.12.006

DOI

10.1016/j.mpdhp.2023.12.006

URI

https://hdl.handle.net/20.500.14709/132