Cataract Surgery Outcomes in Retinitis Pigmentosa A Comparative Clinical Database Study

Purpose: To report visual acuity (VA) outcomes, intraoperative and postoperative complications of isolated cataract surgery in eyes with retinitis pigmentosa (RP), compared with non-RP-affected eyes. Design: Retrospective clinical cohort study. Methods: A total of 113,389 eyes underwent cataract surgery between July 2003 and March 2015 at 8 clinical sites in the United Kingdom. Eyes with RP as the only comorbid pathology and eyes without any ocular comorbidities (controls) undergoing cataract surgery were compared. VA at 4 to 12 weeks postoperatively and rates of intraoperative and postoperative complications are reported. Results: Seventy-two eyes had RP. The mean age in the RP group was 57 ± 15 compared to 75 ± 10 in controls (P < .001). Females represented 46% of RP cases and 60% of controls (P = .06). Preoperative VA (mean LogMAR = 1.03 vs 0.59, P < .001) and postoperative VA (0.71 vs 0.14, P < .001) were worse in RP group. The mean VA gain was 0.25 ± 0.60 LogMAR in RP vs 0.43 ± 0.48 LogMAR in controls (P < .001). There were no significant differences in the rate of intraoperative pupil expansion use, posterior capsular tears, or zonular dialysis. Postoperative cystoid macular edema developed in 6.9% of RP eyes and 1% of controls (P < .001). The need for IOL repositioning or exchange was not statistically different between the two groups. Conclusion: Cataract surgery can improve vision in eyes with RP and cataract. Intraoperative complications were similar to control eyes; however, RP eyes experienced more frequent postoperative cystoid macular edema.

Citation

Georgiou, M., Shakarchi, A. F., Elhusseiny, A. M., Michaelides, M., & Sallam, A. B. (2024). Cataract Surgery Outcomes in Retinitis Pigmentosa A Comparative Clinical Database Study. American journal of ophthalmology, 262, 34–39. https://doi.org/10.1016/j.ajo.2024.01.037

DOI

10.1016/j.ajo.2024.01.037

URI

https://hdl.handle.net/20.500.14709/158

Usage rights

CC BY 4.0

License

https://creativecommons.org/licenses/by/4.0/