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Publication RCEM best practice guideline: suspected cannabinoid hyperemesis syndrome in emergency departments(BMJ Publishing Group, 2024-03-06) Humphries, Christopher; Gillings, Marianne; Gillings, Marianne; Medical and DentalCannabinoid hyperemesis syndrome (CHS) is an episodic syndrome of cyclic vomiting in the context of the prolonged use of cannabis. The Royal College of Emergency Medicine Toxicology Special Interest Group has produced guidance to support emergency medicine clinicians with the recognition and treatment of people experiencing CHS.Considerations regarding recognition, investigation and communication are discussed, and recommendations regarding treatment options (which include haloperidol and capsaicin) are made. There is a focus on making recommendations on the best available evidence.